Kano H, Kato Y, Fukui S, Maruyama S, Kobayashi T: Development of a surgical ciliated cysts after maxillary sinus floor augmentation for dental implants: a case report and review of the literature. J Oral Maxillofac Surg Med Pathol 37: 1018-1021, 2025.
Takamura K, Ajioka Y, Abé T, Gritcun T, Takashima S, Kondo S, Tani Y, Ohashi R: Progression of dysplasia in sessile serrated lesions with proliferative zone redistribution: “Top-down growth” as a marker of malignant potential. Virchows Arch 487: 389-99, 2025.
Yamagata Y, Takahashi T, Ohshima S, Omata J, Yokoyama Y, Shodo R, Ueki Y, Abé T, Umezu H, Horii A: Pre-epiglottic adenocarcinoma NOS presenting as a cystic mass: a diagnostic challenge and surgical management. Oral Oncol 167: 107451, 2025.
Kurita H, Uzawa N, Nakayama H, Abe T, Ibaraki S, Ohyama Y, Uchida K, Sato H, Miyabe S, Abé T, Kakimoto N, Kaida A, Sugiura T, Kioi M, Danjo A, Kitamura N, Hasegawa O, Tanaka T, Ueda N, Hasegawa T, Asoda S, Katsuta H, Yanamoto S, Yamada S, Takeda D, Suzuki T, Ohta Y, Kirita T: Japanese clinical practice guidelines for oral cancer, 2023. Int J Oral Maxillofac Surg 54: 461-76, 2025.
Imai Y, Kishimoto N, Koyama Y, Sango K, Takeuchi K, Yamazaki M, Tanuma J, Tran SD, Seo K: Effects of Adipose-Derived Stem Cell Extract on Peripheral Nerve Cells. Cureus 17(10): e94180, 2025.
Haga K, Kamimura Y, Yamazaki M, Funayama A, Saito Y, Kida M, Tanuma J, Izumi K: Quantitative and longitudinal monitoring of cancer cell invasion in a three-dimensional in vitro model of oral cancer using optical coherence tomography. Sci Rep 15: 45449, 2025.
Sakurai K, Tomihara K, Yamazaki M, Tanuma J, Yamada S: High CD36 Expression Predicts Aggressive Invasion and Recurrence in Oral Squamous Cell Carcinoma. Int J Mol Sci 26(24): 12071, 2025.
その他 Miscellaneous
阿部達也: 口腔扁平上皮癌の側方上皮内進展と間質浸潤:病理学的解析とその相反制御に関わる因子. Medical Science Digest 51(1): 54-55, 2025.
Zhang L, Sonobe Y, Hirai H, Yamazaki M, Tanuma J, Tomihara K: Integrating machine learning with multi-omics analysis to reveal the prognostic value of perineural invasion in head and neck squamous !l ee carcinoma. 令和7年度新潟歯学会第2回例会, 2025年11月8日, 新潟, 新潟歯学会雑誌 55 (2): 64頁, 2025.
Abé T: Alternative splicing signatures of mRNA in head and neck squamous cell carcinoma and pathological significance: TCGA database analysis. SGPath/SSPath 90th annual congress 2025, 2025年11月20-22日, Zurich, program: 20頁, 2025.
Haga K, Maruyama S, Yamazaki M, Abé T, Tanuma J: Identification of early detection markers of oral potentially malignant disorders and oral squamous cell carcinoma using oral liquid-based cytology. The 22nd International Congress of Cytology, 2025年5月11-14日 Firenze, program: 25頁, 2025.
Fujii S, Hasegawa K, Maehara T, Kurppa KJ, Heikinheimo K, Warner KA, Maruyama S, Tajiri Y, Nör JE, Tanuma J, Kawano S, Kiyoshima T: Wnt/β-catenin-c-kit axis may play a role in adenoid cystic carcinoma prognostication. Pathology Research and Practice 254: 155148, 2024.
Haga K, Funayama A, Yamazaki M, Maruyama S, Hara T, Saito N, Saito D, Sotsuka Y, Hayashi T, Tanuma J, Kobayashi T: Extensive ameloblastic fibroma of the mandible in an elderly woman: A case report and review of the literature. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 36 (3): 333–340, 2024.
Kobayashi R, Hirai H, Maruyama S, Tanuma J, Tomihara K: Oral Focal Mucinosis of the Tongue: Case Report and Review of the Literature. Cureus 16(8): e67882, 2024
Takaichi M, Tachinami H, Takatsuka D, Yonesi A, Sakurai K, Rasul MI, Imaue S, Yamada S, Ruslin M, Yamazaki M, Tanuma J, Noguchi M, Tomihara K: Targeting CD36-Mediated Lipid Metabolism by Selective Inhibitor-Augmented Antitumor Immune Responses in Oral Cancer. International Journal of Molecular Sciences 25(17): 9438, 2024.
Kawasaki M, Kawasaki K, Sari FT, Kudo T, Nihara J, Kitamura M, Nagai T, Utama V, Ishida Y, Meguro F, Kesuma A, Fujita A, Nishimura T, Kogure Y, Maruyama S, Tanuma J, Kakihara Y, Maeda T, Ghafoor S, Khonsari RH, Corre P, Sharpe PT, Cobourne M, Franco B, Ohazama A: Cell-cell interaction determines cell fate of mesoderm-derived cell in tongue development through Hh signaling. eLife 13: e85042, 2024.
Akimori Y, Yamazaki M, Maruyama S, Abé T, Tomihara K, Maeda T, Tanuma J: Searching for new early detection markers of oral epithelial dysplasia and oral squamous cell carcinoma using oral liquid-based cytology. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 36(4): 624-631, 2024.
Yonesi A, Tomihara T, Takatsuka D, Tachinami H, Yamazaki M, Jadidi ARY, Takaichi M, Imaue S, Fujiwara K, Yamada S, Tanuma J, Noguchi M: Rapamycin induces phenotypic alterations in oral cancer cells that may facilitate antitumor T cell responses. Biomedicines 12(5), 1078, 2024.
Takatsuka D, Tachinami H, Suzuki N, Yamazaki M, Yonesi A, Takaichi M, Imaue S, Yamada S, Tanuma J, Noguchi M, Tomihara K: PAK4 inhibition augments anti‑tumour effect by immunomodulation in oral squamous cell carcinoma. Scientific Reports 14: 14092, 2024.
Hayashi K, Takagane K, Itoh G, Kuriyama S, Koyota S, Meguro K, Ling Y, Abé T, Ohashi R, Yashiro M, Mizuno M, Tanaka M: Cell-cell contact-dependent secretion of large-extracellular vesicles from EFNB high cancer cells accelerates peritoneal dissemination. British Journal of Cancer 13(6): 982-995, 2024.
Naito E, Igawa K, Takada S, Haga K, Yortchan W, Suebsamarn O, Kobayashi R, Yamazaki M, Tanuma J, Hamano T, Shimokawa T, Tomihara K, Izumi K: The effect of carbon‑ion beam irradiation on three‑dimensional in vitro models of normal oral mucosa and oral cancer: development of a novel tool to evaluate cancer therapy. In Vitro Cellular & Developmental Biology – Animal 60(10): 1184-1199, 2024.
Abé T, Yamazaki M, Nozumi M, Maruyama S, Takamura K, Ohashi R, Ajioka Y, Tanuma J: Ladinin-1 in actin arcs of oral squamous cell carcinoma is involved in cell migration and epithelial phenotype. Scientific Reports 14: 22778, 2024.
Aizawa Y, Haga K, Yoshiba N, Yortchan W, Takada S, Tanaka R, Naito E, Abé T, Maruyama S, Yamazaki M, Tanuma J, Igawa K, Tomihara K, Togo S, Izumi K: Development and characterization of a three-dimensional organotypic in vitro oral cancer model with four co-cultured cell types, including patient-derived cancer-associated fibroblasts. Biomedicines 12(10), 2373, 2024.
Kurita H, Uzawa N, Nakayama H, Abe T, Ibaraki S, Ohyama Y, Uchida K, Sato H, Miyabe S, Abé T, Kakimoto N, Kaida A, Sugiura T, Kioi M, Danjo A, Kitamura N, Hasegawa O, Tanaka T, Ueda N, Hasegawa T, Asoda S, Katsuta H, Yanamoto S, Yamada S, Takeda D, Suzuki T, Ohta Y, Kirita T: Japanese clinical practice guidelines for oral cancer, 2023. International Journal of Oral & Maxillofacial Surgery 54(5): 461-476, 2024.
Kano H, Kato Y, Kobayashi T, Maruyama S: Methotrexate-associated lymphoproliferative disorder causing osteonecrosis of the jaw: a case report. Niigata Dent. J. 54(2): 15-21, 2024
Suda D, Funayama A, Niimi K, Sakuma H, Saito D, Hayashi T, Maruyama S, Tanuma J, Kobayashi T. Pancreatic adenocarcinoma diagnosed by metastasis to the mandibular gingiva: A case report. 口腔腫瘍 36(4): 89-95, 2024.
学会発表 Presentations
Haga K, Funayama A, Saito N, Saito D, Sakuma H, Suda A, Yakeuchi R, Hayashi T, Tanuma J, KobayashiT:Computer-assisted surgery in mandibular reconstruction and a patient-specific mandibular reconstruction plate. International Collaborative Symposium on Development of Human Resources in Practical Oral Health and Treatment 2024. May 31- June 1, 2024, Bangkok, Thailand. Program Book: p.91, 2024.
Maruyama S, Yamazaki M, Abé T, Kato Y, Kano H, Tanuma J. Liquid-based cytology for differentiating two cases of pemphigus vulgaris from oral squamous cell carcinoma. Daig Cytol, 51 (5): E170-E175, 2023.
Maruyama S, Yamazaki M, Abé T, Cheng J, Saku T, Tanuma J: Hypoxia-Induced Biosynthesis of the Extracellular Matrix Molecules, Perlecan and Fibronectin, Promotes the Growth of Pleomorphic Adenoma Cells In Vitro Models. Biomedicines, 11(11): 2981, 2023.
Akimori T, Yamazaki M, Abé T, Maruyama S, Tomihara K, Maeda T, Tanuma J: Searching for new early detection markers of oral epithelial dysplasia and oral squamous cell carcinoma using oral liquid-based cytology. J Oral Maxillofac Surg Med Pathol, November 25, 2023. (in press)
Takamura M, Nikkuni Y, Hayashi T, Katsura K, Nishiyama H, Yamazaki M, Maruyama S, Tanuma J: Comparing the Diagnostic Accuracy of Ultrasonography, CT, MRI, and PET/CT in Cervical Lymph Node Metastasis of Oral Squamous Cell Carcinoma. Biomedicines, 11(12): 3119, 2023.
Maruyama S, Yamazaki M, Abé T, Kato Y, Kano H, Tanuma J. Liquid-based cytology for differentiating two cases of pemphigus vulgaris from oral squamous cell carcinoma. Daig Cytol, 51 (5): E170-E175, 2023.
Katagiri W, Saito D, Maruyama S, Ike M, Nishiyama H, Hayashi T, Tanuma J, Kobayashi T: Masticatory muscle tendon-aponeurosis hyperplasia that was initially misdiagnosed for polymyositis: a case report and review of the literature. Plast. Reconstr. Surg, 45(1): 18, 2023.
Chan NN, Yamazaki M, Maruyama S, Abe T, Haga K, Kawaharada M, Izumi K, Kobayashi T, Tanuma J. Cholesterol Is a Regulator of CAV1. Localization and Cell Migration in Oral Squamous Cell Carcinoma. Int J Mol Sci, 24(7), 2023.
その他 Miscellaneous
田沼順一: お口に気になるものがあれば、口腔細胞診(歯科検診)はいかがでしょうか?Niigata University Web Magazine 教員コラム(六花), 2023年5月23日.
Yamazaki M: Keynote Speech 7 Dead tumor cells: Driving for progression of oral squamous cell carcinoma. The 21st International congress of oral pathology and medicine, Aug 17-21, 2023, Taiwan. Program & Abstract Book, 40-41, 2023.
Nagai T, Yamazaki M, Nishikawa A, Kodama Y, Nishiyama H, Hayashi T, Tanuma J, Takagi R, Tomihara K. Rosai-Dorfman disease of the maxilla: A rare report and literature review. J Oral Maxillofac Surg Med Pathol, 34; 665-671, 2022.
Kawaharada M, Yamazaki M, Maruyama S, Abé T, Nyein Nyein Chan , Kitano T, Kobayashi T, Maeda T, Tanuma J. Clinicopathologic factors influencing the screening accuracy of oral cytology: A retrospective cohort study. Oncol Lett, 24 (5): 385, 2022.
Abé T, Yamazaki M, Maruyama S, Ikeda N, Sumita Y, Tomihara K, Tanuma J.Adenosquamous Carcinoma with the Acantholytic Feature in the Oral Cavity: A Case Report and Comprehensive Literature Review. Diagnostic, 12: 2398, 2022.
Chan NN, Yamazaki M, Hayashi T, Kobayashi T, Tanuma J. Solitary central osteoma of the mandible with unusual clinicoradiological presentations: a case report and literature review. Oral Sci Int, July 1-7, 2022.
Maruyama S, Yamazaki M, Abé T, Kato Y, Kano H, Tanuma J. Liquid-based cytology for differentiating two cases of pemphigus vulgaris from oral squamous cell carcinoma. Daig Cytol, 51 (5): E170-E175, 2023.
Chan NN, Yamazaki M, Maruyama S, Abe T, Haga K, Kawaharada M, Izumi K, Kobayashi T, Tanuma J. Cholesterol Is a Regulator of CAV1. Localization and Cell Migration in Oral Squamous Cell Carcinoma. Int J Mol Sci, 24(7), 2023.
Maeda SI, Fujiwara K, Tomihara K, Yamazaki M, Imaue S, Noguchi M. A case of anti-laminin 332 mucous membrane pemphigoid manifesting as desquamative gingivitis. Oral Science International, 18 (1): 73-77, 2021.
Kiguchi T, Kakihara Y, Yamazaki M, Katsura K, Izumi K, Tanuma J, Saku T, Takagi R, Saeki M. Identification and characterization of R2TP in the development of oral squamous cell carcinoma. Biochemical and Biophysical Research Communications, 548 : 161-166, 2021.
Haga K, Yamazaki M, Maruyama S, Kawaharada M, Suzuki A, Hoshikawa E, Chan NN, Izumi K, Tanuma JI. Crosstalk between oral squamous cell carcinoma cells andcancer-associated fibroblasts via the TGF-β/SOX9 axis in cancer progression. Translational Oncology, 14 (12): 101236, 2021.
Kawaharada M, Maruyama S, Abé T, Yamazaki M, Kurokawa A, Katagiri W, Takagi R, Hayashi T, Kobayashi T, Tanuma J. Other iatrogenic immunodeficiency-associated lymphoproliferative disorders in the oral cavity: a clinicopathologic study of 4 cases and literature review. Oral Surgery Oral Medicine, Oral Pathology and Oral Radiology, 132 (6): 687-697, 2021.
症例報告 Case Reports
Kawaharada M, Katagiri W, Maruyama S, Nishiyama H, hayashi T, Kobayashi T, Tanuma J. Low-grade myofibroblastic sarcoma of the tongue with difficulty of diagnosis: A case report and review of the literature. Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 33 (1): 93-47,2021.
Maruyama S, Mori T, Yamazaki M, Abé T, Ryo E, Kano H, Hasegawa G, Tanuma JI. Central mucoepidermoid carcinoma arising directly from a glandular odontogenic cyst of the mandible: a case report. Diagnostic Pathology.16(1):61,2021. doi: 10.1186/s13000-021-01124-0.
Yamazaki M, Maruyama S, Abé T, Sumita Y, Katsumi Y, Nikkuni Y, Hayashi T, Tanuma JI. Spindle cell squamous cell carcinoma exhibiting prominent neutrophil phagocytosis: a case report. Journal of Medical Case Report. 15:438, 2021. doi: 10.1186/s13256-021-03066-z.
Takeuchi R, Funayama A, Oda Y, Abé T, Yamazaki M, Maruyama S, Hyashi T, Tanuma J, Kobayashi T.Melanotic neuroectodermal tumor of infancy in the mandible: A case report. Medicine, 100:50, 2021.
その他 Miscellaneous
Tanuma J: Role of TGFβ/SOX9 axis in carcinogenesis in vitro and in vivo models. NEWS RELEASE. EurekAlert!. AAAS. 24-Oct-2021.
Sakurai K, Nakamori K, Yamazaki M, Tanuma J. Corrigendum to “An ectomesenchymal chondromyxoid tumour on the lateral border of the tongue” [Int J Oral Maxillofac Surg 49 (2020) 1290–1203]. International Jounal of Oral and Maxillofacial Surgery, 50 (12): 1653. 2021.
Takamura M, Kobayash T, Nikkuni Y, Kouji Katsura K, Yamazaki M, Maruyama S, Tanuma J, Hayashi T. A comparative study between CT, MRI, and intraoral US for the evaluation of the depth of invasion in early stage (T1/T2) tongue squamous cell carcinoma. The 23rd international Congress of DentoMaxillofacial Radiology. April 28 - May 1, 2021. Gwangju, Kore.
Sakurai K, Tomihara K, Yamazaki M, Heshiki W, Moniruzzaman R, Sekido K, Tachinami H, Ikeda A, Imaue S, Fujiwara K, Noguchi M. CD36 expression on oral squamous cell carcinoma cells correlates with enhanced proliferation and migratory activity. Oral Diseases, 26 (4): 745-755, 2020.
Yamazaki M, Maruyama S, Abé T, Tsuneki M, Kato H, Izumi K, Tanuma JI, Cheng J, Saku T. Rac1-dependent phagocytosis of apoptotic cells by oral squamous cell carcinoma cells: A possible driving force for tumor progression. Experimental Cell Research, 392 (1): 112013, 2020.
Abé T, Kitagawa N, Yoshimoto S, Maruyama S, Yamazaki M, Inai T, Hashimoto S, Saku T. Keratin 17-positive Civatte bodies in oral lichen planus-distribution variety, diagnostic significance and histopathogenesis. Scientific Reports, 10:14586, 2020.
症例報告 Case Reports
Sakurai K, Nakamori K, Yamazaki M, Tanuma JI. An ectomesenchymal chondromyxoid tumour on the lateral border of the tongue. International Journal of Oral and Maxillofacial Surgery, 49 (10): 1290-1293, 2020.
Haga K, Yamazaki M, Maruyama S, Suzuki A, Hoshikawa E, Funayama A, Mikami T, Kobayashi T, Izumi K, Tanuma J: Cancer-associated fibroblasts promote the invasion of oral squamous cell carcinoma cells via the TGF-β/SOX9 axis. International collaborative symposium on Development of human resources in practical oral health and treatment, Bali, Indonesia, Feb10-12, 2020. Program book, 55, 2020.